Publications by Dr. Manoj Motwani of Cornea Revolution


A protocol for topographic-guided corneal repair utilizing the US Food and Drug Administration- approved Wavelight Contoura

Conclusion: Contoura measured refraction can be integrally used as part of the San Diego Protocol to safely repair highly warped corneas. The refractive outcomes show dramatic improvement in vision, best-corrected visual acuity (BCVA), refraction, and topographic uniformity.

Keywords: corneal ablation, laser-assisted in situ keratomileusis, photorefractive keratectomy, refractive surgery, corneal irregularity, corneal trauma, decentered excimer laser ablations, radial keratotomy, higher order aberrations

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Analysis and Causation of All Inaccurate Outcomes After WaveLight Contoura LASIK with LYRA Protocol

Conclusion: The causes of the majority of inaccurate outcomes have not been properly
defined and must be incorporated into further improving outcomes. Current and planned
advances in technology do not address the majority of these causes.

Keywords: astigmatism, corneal epithelium, femtosecond laser, higher-order aberration,
LASIK, refractive error; Contoura; topography guided ablation; LYRA protocol

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Biomechanical Changes to the Cornea from LASIK Flap Creation Resulting in Inaccurate Ablations and Suboptimal Refractive Outcomes with Topographic-Guided Ablation

Conclusion: A biomechanical change during flap creation can occur in certain types of
corneas during LASIK flap creation and subsequent treatment with topographic-guided
ablation leading to an irregular ablation and suboptimal refractive outcomes.

Keywords: corneal epithelium, femtosecond laser, higher order aberration, laser ablation,
laser in-situ keratomileusis, LASIK

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Photorefractive Keratectomy After Late Traumatic LASIK Flap Loss

Conclusions: Treating a patient with traumatic LASIK fl ap loss can be done by careful, conservative treatment of the abrasion followed by correction of the refractive error using PRK with MMC. [J Refract Surg. 2011;27(7):542-544.]

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Predictions of Residual Astigmatism from Surgical Planning for Topographic-Guided LASIK Based on Anterior Corneal Astigmatism (LYRA Protocol) vs the Phorcides Analytic Engine

Conclusion: Phorcides was significantly less accurate in surgical planning than the LYRA
Protocol overall and a 51% of primary patients could have a likelihood of significant residual
astigmatism. Phorcides would also have provided a less accurate outcome in the majority of
patients that needed secondary enhancement.

Keywords: Contoura, topographic-guided ablation, LYRA Protocol, Phorcides, uniform

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Response to: WaveLight® Contoura topographyguided planning: contribution of anterior corneal higher-order aberrations and posterior corneal astigmatism to manifest refractive astigmatism

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The use of WaveLight Contoura to create a uniform cornea: 6-month results with subjective patient surveys

Conclusion: Contoura measured axis and astigmatism-eliminated HOA, resulting in a more uniform cornea with an accurate removal of astigmatism, excellent 20/15 and 20/20 visual outcomes, and favorable patient-reported subjective outcomes.

Keywords: astigmatism, WaveLight Contoura, topography-guided ablation, LASIK, cornea, Contoura with LYRA protocol

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The use of WaveLight® Contoura to create a uniform cornea: the LYRA Protocol. Part 1: the effect of higher-order corneal aberrations on refractive astigmatism

Conclusion: Higher-order aberrations interacting with lower-order astigmatism is the main reason for the differences between manifest refraction and Contoura measured astigmatism, and the linkage between these interactions can be successfully treated using Contoura and the LYRA Protocol. Lenticular astigmatism is relatively rare.

Keywords: topographic guided ablation, LASIK, PRK, WaveLight Contoura, uniform cornea, higher order aberrations

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The use of WaveLight® Contoura to create a uniform cornea: the LYRA Protocol. Part 2: the consequences of treating astigmatism on an incorrect axis via excimer laser

Conclusion: Correction of an incorrect manifest refraction astigmatic axis does not simply create undercorrection of the astigmatism but induces an entirely new abnormal astigmatism on a different axis. Manifest refraction is less accurate and can lead to abnormal astigmatism when laser ablation is performed.

Keywords: WaveLight Contoura, astigmatism treatment, asymmetric astigmatism, topographic guide ablation, higher order aberrations, Contoura with LYRA Protocol, LASIK, PRK

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The use of WaveLight® Contoura to create a uniform cornea: the LYRA Protocol. Part 3: the results of 50 treated eyes

Conclusions: Using WaveLight® Contoura measured astigmatism and axis removes higher order aberrations and allows for the creation of a more uniform cornea with accurate removal of astigmatism, and reduction of aberration polynomials. WaveLight® Contoura successfully links the refractive correction layer and aberration repair layer using the Layer Yolked Reduction of Astigmatism Protocol to demonstrate how aberration removal can affect refractive correction.

Keywords: WaveLight Contoura, topographic guided ablation, LASIK, PRK, uniform cornea, Contoura with LYRA Protocol, measured astigmatism

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Topographic-guided treatment of hyperopic corrections with a combination of higher order aberration removal with WaveLight® Contoura and wavefront-optimized hyperopic treatment

Conclusion: This pilot study demonstrated that more uniform corneas can be created while treating hyperopic corrections, but a high level of secondary corrections were needed.

Keywords: Contoura, topographic guided ablation, hyperopia, LYRA Protocol

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Treatment of high myopia/myopic astigmatism with a combination of WaveLight Contoura with LYRA protocol and wavefront-optimized treatment

Conclusion: Treatment of high myopia/astigmatism with this combination of Contoura with LYRA protocol and WFO results in excellent visual outcomes, large ablation zones on topography, and few subjective reported night vision issues.

Keywords: Contoura, topographic guided ablation, high myopia, ICL, WaveLight lasers, LYRA Protocol

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Treatment of moderate-to-high hyperopia with the WaveLight Allegretto 400 and EX500 excimer laser systems

Conclusions: Both the 400 and 500 Hz excimer laser systems were safe and effective for the LASIK treatment of moderate-to-high hyperopia. The overall rate of regression was low and the amount of regression was relatively small with both systems.

Keywords: excimer laser, hyperopia, laser-assisted in situ keratomileusis, LASIK, regression

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